The Makerere University Walter Reed Program (MUWRP) Clinical Research Site (CRS) based in Kampala, Uganda, is one of the many international medical research initiatives that focuses on combatting infectious disease threats.
In 2009, MUWRP and WRAIR launched the first Ebola vaccine clinical trial conducted in Africa. Since then the site has been involved with the trials of four more Ebola vaccine candidates at various stages of development.
EIDB and Makerere University-Walter Reed Project (MUWRP) launched a Phase 1 clinical trial in 2019 to evaluate the safety and immunogenicity of an Ebola vaccine candidate against the Sudan species of the virus in healthy adult volunteers in Uganda.
The program supports a variety of Phase 1-3 clinical trials as well as non-clinical research such as prospective cohort studies and program evaluations. The site boasts 16 years of experience in conducting IND clinical trials and a staff with extensive research backgrounds and proven skill with collecting high quality data.
The Joint Mobile Emerging Disease Intervention Clinical Capability (JMEDICC), at the Fort Portal Regional Referral Hospital, provides a platform for clinical trials during filovirus (Ebola/ Marburg) outbreaks, allowing testing of new therapeutics or medical countermeasures.